DRM3 Antibody

Datasheet

Code	CSB-PA265323XA01DOA
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) DRM3 Polyclonal antibody

Uniprot No.

Q8H1E8

Target Names

DRM3

Alternative Names

DRM3 antibody; At3g17310Probable inactive DNA antibody; cytosine-5)-methyltransferase DRM3 antibody; Protein DOMAINS REARRANGED METHYLTRANSFERASE 3 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana DRM3 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Catalytically inactive DNA methyltransferase that acts as regulatory factor for DRM2-mediated DNA methylation. Required for maintenance of non-CpG DNA methylation. Required for normal establishment and maintenance of RNA-directed DNA methylation (RdDM) and accumulation of specific repeat-associated small interfering RNAs (siRNAs). Required for nucleolus organizer region (NOR) nuclear organization during interphase. Acts downstream of the production of siRNAs. May promote RNA polymerase V (Pol V) transcriptional elongation or assist in the stabilization of Pol V transcripts.

Gene References into Functions

DRM3 and DRM2 are both required for NOR loci nuclear organization but not for overall peri and centromeric heterochromatin organization. PMID: 25316414
Data show that despite catalytically mutated, DRM3 (At3g17310) is required for normal maintenance of non-CG DNA methylation, establishment of RNA-directed DNA methylation triggered by repeat sequences and accumulation of repeat-associated small RNAs. PMID: 21060858

Subcellular Location

Nucleus.

Protein Families

Class I-like SAM-binding methyltransferase superfamily, DRM-methyltransferase family

Database Links

KEGG: ath:AT3G17310

STRING: 3702.AT3G17310.1

UniGene: At.5773

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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