grh Antibody

1. Grh and Vvl participate in a regulatory network controlling epithelial maturation. PMID: 28760809
2. Grh remains bound to at least 1146 genomic loci over days of development. Grh binds to target genes well before the Grh-dependent transcriptional program commences. PMID: 28007888
3. The transcription factor Grainy head and the steroid hormone ecdysone drive the production of two partially overlapping sets of cuticle factors. PMID: 22458773
4. results suggest that Grh acts as an activator to support expression of ind, which was surprising as we identified this factor using an element that mediates dorsally-localized repression PMID: 22216201
5. Phosphorylation of Grainy head by ERK is essential for wound-dependent regeneration but not for development of an epidermal barrier PMID: 21187384
6. Data show that apical membrane enlargement is critical for lumenal elongation of the Drosophila airways, and is independently controlled by the transcription factor Grainy head, whose activity is upregulated by Branchless. PMID: 12466193
7. In the abdomen, Grh terminates neural proliferation by regulating the competence of neuroblasts to undergo apoptosis in response to Abdominal-A expression PMID: 16049114
8. Grainy head is essential for post-embryonic neuroblasts to adopt the stem cell program appropriate to their position within the central nervous system; furthermore, ectopic expression of Grh is sufficient to promote ectopic E-cadherin. PMID: 16275038
9. the grainyhead gene, which encodes a DNA binding protein, interacts with one Polycomb response element of the bithorax complex PMID: 16449654
10. The level of Grh-mediated transcriptional wound responses is activated by Stit upon wounding coordinates cytoskeletal rearrangements. PMID: 19525935

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KEGG: dme:Dmel_CG42311

STRING: 7227.FBpp0288984

UniGene: Dm.3595