FEM1B Antibody

Datasheet
Code CSB-PA891718XA01HU
Product Type Polyclonal Antibody
Uniprot No. Q9UK73
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Homo sapiens (Human) FEM1B protein
Raised in Rabbit
Species Reactivity Homo sapiens (Human)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugate
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Protein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha) FEM1B F1AA KIAA0396
Immunogen Species Homo sapiens (Human)
Gene Names FEM1B
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
Subcellular Location Cytoplasm, Nucleus
Protein Families Fem-1 family
Tissue Specificity Widely expressed. Highly expressed in testis. Weakly expressed in other tissues.
Database Links

HGNC: 3649

OMIM: 613539

KEGG: hsa:10116

STRING: 9606.ENSP00000307298

UniGene: Hs.362733

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