FEM1B Antibody

Datasheet
Code CSB-PA008582GA01HU
Product Type Purified Rabbit Anti human PolyClonal Antibody
Size US$685
Uniprot No. Q9UK73
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Human FEM1B
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,IHC
Storage Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity Purified
Isotype IgG
Alias fem-1 homolog b (C. elegans);FEM1B;DKFZp451E0710;FIAA ;
Immunogen Species Homo sapiens (Human)
Target Names FEM1B
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
HGNC 3649
RGD 1304569
MGI 1335087
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Function Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
Subcellular Location Cytoplasm, Nucleus
Protein Families Fem-1 family
Tissue Specificity Widely expressed. Highly expressed in testis. Weakly expressed in other tissues.
Database Links

HGNC: 3649

OMIM: 613539

KEGG: hsa:10116

STRING: 9606.ENSP00000307298

UniGene: Hs.362733

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