FKTN Antibody

Code CSB-PA008709ZA01MOV
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Product Details

Full Product Name
Rabbit anti-Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) FKTN Polyclonal antibody
Uniprot No.
Target Names
FKTN
Alternative Names
Fukutin (EC 2.-.-.-), FKTN, FCMD
Raised in
Rabbit
Species Reactivity
Macaca fascicularis
Immunogen
Recombinant Macaca fascicularis FKTN protein
Immunogen Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Conjugate
Non-conjugate
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-beta-1. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development.
Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein. Cytoplasm. Nucleus.
Protein Families
LicD transferase family
Tissue Specificity
Expressed in the retina (at protein level).
Database Links

UniGene: Mfa.10927

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