FMO5 Antibody

Code CSB-PA008751XA01RB
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Product Details

Full Product Name
Rabbit anti-Oryctolagus cuniculus (Rabbit) FMO5 Polyclonal antibody
Uniprot No.
Target Names
FMO5
Alternative Names
FMO5Dimethylaniline monooxygenase [N-oxide-forming] 5 antibody; EC 1.14.13.8 antibody; Dimethylaniline oxidase 5 antibody; FMO 1C1 antibody; FMO form 3 antibody; Hepatic flavin-containing monooxygenase 5 antibody; FMO 5 antibody
Raised in
Rabbit
Species Reactivity
Oryctolagus cuniculus (Rabbit)
Immunogen
Recombinant Oryctolagus cuniculus (Rabbit) FMO5 protein
Immunogen Species
Oryctolagus cuniculus (Rabbit)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms. Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity. Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects.
Subcellular Location
Microsome membrane. Endoplasmic reticulum membrane.
Protein Families
FMO family
Tissue Specificity
Kidney and liver.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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