LAMB Antibody

^{Rare Species}

Datasheet

Code	CSB-PA365810XA01ENV
Size	US$299
Image	Western Blot Positive WB detected in Recombinant protein All lanes: LAMB antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 29.8 kDa Observed band size: 31 kDa
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Target Background

Product Details

Full Product Name

Rabbit anti-Escherichia coli (strain K12) lamB Polyclonal antibody

Uniprot No.

P02943

Target Names

lamB

Alternative Names

lamB antibody; malB antibody; b4036 antibody; JW3996 antibody; Maltoporin antibody; Lambda receptor protein antibody; Maltose-inducible porin antibody

Raised in

Rabbit

Species Reactivity

Escherichia coli (strain K12)

Immunogen

Recombinant Escherichia coli (strain K12) LAMB protein

Immunogen Species

Escherichia coli (strain K12)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Protein A/G

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

The production of the LAMB polyclonal antibody involves introducing recombinant Escherichia coli (strain K12) LAMB protein into a rabbit, which triggers the production of antibodies that specifically target this antigen. Antibody production is further amplified through a booster injection, and the resulting LAMB polyclonal antibodies in the rabbit's serum are collected and purified using protein A/G. Rigorous testing conducted in ELISA and WB assays has conclusively demonstrated the LAMB antibody's precise ability to recognize Escherichia coli (strain K12) LAMB protein.

The Escherichia coli (strain K12) LAMB protein serves as a component of the bacterial outer membrane. It is involved in maintaining the structural integrity of the outer membrane and plays a role in the transport of molecules across the membrane. Additionally, the LAMB protein is also known to be involved in bacterial adhesion and biofilm formation.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Identification of Receptors and Lysis Inhibition Mechanism of the Polyvalent Bacteriophage CSP1 in Cronobacter sakazakii and Escherichia coli 김무성,Thesis & Dissertation,2025

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Target Background

Function

Involved in the transport of maltose and maltodextrins. Indispensable for translocation of maltodextrins (alpha 1-4 linked polyglucosyls) containing more than three glucosyl moieties. A hydrophobic path ('greasy slide') of aromatic residues serves to guide and select the sugars for transport through the channel. Also acts as a receptor for several bacteriophages including lambda. Binds maltosaccharides; when LamB binds starch in soft agar, it inhibits motility.

Gene References into Functions

Our data indicate that the negative regulation by LamB is widely detected in antibiotic-resistant E. coli. LamB serves as a porin to influx an antibiotic and is interacted with Odp1. PMID: 24412198
Results report the crystallization of E. coli maltoporin in a new crystal form; the crystals belonged to the trigonal R3 space group and diffracted to 1.9 A resolution. PMID: 21206039
downregulation of LamB expression in the CTC-resistant E. coli strain and the increased antibiotic resistance in its gene-deleted strain suggested a negative regulation mechanism in E. coli in response to CTC PMID: 20718490
demonstrated that LamB moves along the bacterial surface and that these movements are restricted by an underlying dynamic spiral pattern PMID: 15341654
all aromatic residues provide some steric hindrance for ion transport through LamB PMID: 16095613

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Subcellular Location

Cell outer membrane; Multi-pass membrane protein.

Protein Families

Porin LamB (TC 1.B.3) family

Database Links

KEGG: ecj:JW3996

STRING: 316385.ECDH10B_4225

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Service

Phage Display Service

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Protein Service

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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LAMB Antibody

Product Details

Citations

Related Products

Customer Reviews and Q&A

Target Background