LAP3 Antibody

Code CSB-PA632987ZA01BO
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Product Details

Full Product Name
Rabbit anti-Bos taurus (Bovine) LAP3 Polyclonal antibody
Uniprot No.
Target Names
LAP3
Alternative Names
LAP3Cytosol aminopeptidase antibody; EC 3.4.11.1 antibody; Leucine aminopeptidase 3 antibody; LAP-3 antibody; Leucyl aminopeptidase antibody; Peptidase S antibody; Proline aminopeptidase antibody; EC 3.4.11.5 antibody; Prolyl aminopeptidase antibody
Raised in
Rabbit
Species Reactivity
Bos taurus
Immunogen
Recombinant Bos taurus LAP3 protein
Immunogen Species
Bos taurus (Bovine)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Cytolosic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.
Gene References into Functions
  1. promoter polymorphism and milk production PMID: 22304649
  2. In this density functional theory study, reaction mechanisms of a co-catalytic binuclear metal center (Zn1-Zn2) containing enzyme leucine aminopeptidase for two different metal bridging nucleophiles (H(2)O and -OH) have been investigated. PMID: 21918843
  3. The LAP3 gene possibly contributed to conducting association analysis and can be used as molecular marker in milk production traits and other performance for animal breeding. PMID: 21110109
Subcellular Location
Cytoplasm.
Protein Families
Peptidase M17 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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