LMP1 Antibody

Code CSB-PA318333ZA01EFE
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Product Details

Full Product Name Rabbit anti-Epstein-Barr virus (strain Raji) (HHV-4) (Human herpesvirus 4) LMP1 Polyclonal antibody
Uniprot No. P13198
Target Names LMP1
Alternative Names LMP1 antibody; BNLF1 antibody; Latent membrane protein 1 antibody; LMP-1 antibody; Protein p63 antibody
Raised in Rabbit
Species Reactivity Epstein-Barr virus
Immunogen Recombinant Epstein-Barr virus LMP1 protein
Immunogen Species Epstein-Barr virus (strain Raji) (HHV-4) (Human herpesvirus 4)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (12-14 weeks)

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Target Background

Function
(From Uniprot)
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins. For example, induces the sumoylation of host IRF7 thereby limiting its transcriptional activity and modulating the activation of innate immune responses. Inhibits also host IFN-alpha-stimulated STAT2 nuclear translocation and interferon-stimulated response element transcriptional activity by interacting with and inhibiting host TYK2.
Subcellular Location Host cell membrane; Multi-pass membrane protein.
Protein Families Herpesviridae LMP-1 family
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