lpxD Antibody

Datasheet

Code	CSB-PA324231XA01ENV
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Target Background

Product Details

Full Product Name

Rabbit anti-Escherichia coli (strain K12) lpxD Polyclonal antibody

Uniprot No.

P21645

Target Names

lpxD

Alternative Names

lpxD antibody; firA antibody; omsA antibody; b0179 antibody; JW0174 antibody; UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase antibody; UDP-3-O-(3-OHC14)-GlcN N-acyltransferase antibody; EC 2.3.1.191 antibody; Protein FirA antibody; Rifampicin resistance protein antibody; UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferase antibody

Raised in

Rabbit

Species Reactivity

Escherichia coli (strain K12)

Immunogen

Recombinant Escherichia coli (strain K12) lpxD protein

Immunogen Species

Escherichia coli (strain K12)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Prefers (3R)-3-hydroxytetradecanoyl-ACP over (3R)-3-hydroxyhexadecanoyl-ACP as the acyl donor in vitro, which is consistent with the structure of E.coli lipid A that contains over 95% (R)-3-hydroxytetradecanoate at the 2 and 2' positions.

Gene References into Functions

The studies highlight key interactions of transient ACP-FabA protein complexes and define the dynamic movements of ACP that facilitate substrate delivery and trigger complex dissociation. PMID: 24771327
these data suggest that unphosphorylated NPr decreases lipid A biosynthesis by inhibiting LpxD activity. PMID: 21605551

Protein Families

Transferase hexapeptide repeat family, LpxD subfamily

Database Links

KEGG: ecj:JW0174

STRING: 316385.ECDH10B_0159

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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lpxD Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background