BIP1 Antibody

Code CSB-PA888748XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) BIP1 Polyclonal antibody
Uniprot No.
Target Names
BIP1
Alternative Names
BIP1 antibody; HSP70-11 antibody; MED37_5 antibody; MED37A antibody; At5g28540 antibody; T26D3.10 antibody; T26D3_50Heat shock 70 kDa protein BIP1 antibody; Heat shock 70 kDa protein 11 antibody; Heat shock protein 70-11 antibody; AtHsp70-11 antibody; Luminal-binding protein 1 antibody; AtBP1 antibody; BiP1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana BIP1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. Involved in polar nuclei fusion during female gametophyte development and is essential for the regulation of endosperm nuclei proliferation. Involved in sperm nuclear fusion with central cell polar nuclei at fertilization, which is critical for normal endosperm nuclear proliferation. Required for pollen development and pollen tube growth. Possesses ATPase activity in vitro.
Gene References into Functions
  1. BIP3 supports the early stages of female gametophyte development, but not polar nuclear fusion, in the absence of BiP1 and BiP2. PMID: 26251880
  2. the bip1 bip2 bip3 triple mutation is lethal in pollen. PMID: 24486762
  3. bip1 bip2 double mutation causes defects in the fusion of polar nuclei during female gametophyte development. PMID: 20080634
Subcellular Location
Endoplasmic reticulum lumen. Nucleus.
Protein Families
Heat shock protein 70 (TC 1.A.33) family, DnaK subfamily
Tissue Specificity
Expressed in mature pollen grains, and pollen tubes.
Database Links

KEGG: ath:AT5G28540

STRING: 3702.AT5G28540.1

UniGene: At.23381

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