Madcam1 Antibody

1. Nkx2-3 deficiency reprograms the endothelial addressin preference for lymphocyte homing in Peyer's patches. PMID: 25320278
2. findings indicate that alpha4beta7*IgG can be used as a probe for functional MAdCAM-1 expressed on HEVs in GALT and could potentially serve as an anti-inflammatory drug inhibiting GALT-specific lymphocyte migration PMID: 21430257
3. ectopic expression of MAdCAM-1 at the BBB does not increase alpha4beta7-integrin-mediated immune cell trafficking into the CNS during MOG(aa35-55)-induced experimental autoimmune encephalomyelitis PMID: 21341265
4. Observed a significant decrease in expression of ICAM-1 and MAdCAM-1 mRNA/protein in lactobacillus plantarum treated colitis. PMID: 19960256
5. results suggest that AT1R regulates the expression of MAdCAM-1 under colonic inflammatory conditions through regulation of the translocation of NF-kappaB into the nucleus PMID: 19940029
6. Lymphocyte binding to MAdCAM-1 via alpha4beta7 integrin activates a signal transduction pathway involving tyrosine phosphorylation of paxillin and p105(Cas-L) PMID: 11947929
7. Mucosal addressin cell adhesion molecule 1 plays an unexpected role in the development of mouse guard hair. PMID: 12230506
8. spatial heterogeneity of MAdCAM-1 and VCAM-1 activation following TNF-alpha challenge may promote specific T lymphocyte recruitment in the inflamed colonic mucosa PMID: 12388196
9. Increased expression of mucosal addressin cell adhesion molecule-1 in gastritis induced by Helicobacter pylori PMID: 12390304
10. expression of MAdCAM-1 by fibroblasts and melanomas suggests MAdCAM-1 may play a role in regulating host responses in the periphery, leucocyte transmigration across nonendothelial boundaries, or the homotypic interactions of some malignant melanomas PMID: 12848854
11. GST-3 is responsible for MECA-79 (MADCAM1)defined luminal ligands PMID: 15111310
12. MAdCAM-1 plays important roles in T-lymphocyte adherence in all intestinal sites. PMID: 15371130
13. In a chronic ileitis model, pathogenic CD4+ T cells use the MAdCAM-1/alpha4beta7 physiologic pathway in order to recirculate to the chronically inflamed small intestine. PMID: 15699171
14. In wild-type mice administered blocking monoclonal antibody (mAb) to VCAM1-1 but nor to Madcam1 recruitment of mast cells to the inflamed lung was not reduced. PMID: 16670268
15. These data indicate that TNF-alpha deficiency alters homoeostasis of the colonic chemokine/cytokine environment and humoral immune response, resulting in an exacerbation of acute DSS-induced colitis in TNF-alpha(-/-) mice. PMID: 17768420
16. Combined effects of diabetes and pregnancy on pancreatic and decidual expression of VCAM-1, MAdCAM-1 and PNAd. PMID: 18031809
17. Expression of MAdCAM-1 in isolated lymphoid follicles (ILFs) of the small intestine colocalizes with CD31 expression, indicating that MAdCAM-1 expression in ILFs is restricted to vascular structures. PMID: 18768861

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STRING: 10090.ENSMUSP00000020554

UniGene: Mm.391556