NAV2 Antibody

Code CSB-PA015479XA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NAV2 Polyclonal antibody
Uniprot No.
Target Names
NAV2
Alternative Names
NAV2 antibody; HELAD1 antibody; KIAA1419 antibody; POMFIL2 antibody; RAINB1 antibody; STEERIN2Neuron navigator 2 antibody; EC 3.6.4.12 antibody; Helicase APC down-regulated 1 antibody; Pore membrane and/or filament-interacting-like protein 2 antibody; Retinoic acid inducible in neuroblastoma 1 antibody; Steerin-2 antibody; Unc-53 homolog 2 antibody; unc53H2 antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens (Human)
Immunogen
Recombinant Homo sapiens (Human) NAV2 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.
Gene References into Functions
  1. NAV2 and CCND2 are novel candidate prognostic markers in uterine leiomyosarcoma and uterine low-grade endometrial stromal sarcoma, respectively. PMID: 28643014
  2. The present study is the first study providing evidence of several genetic variants within the NAV2 gene influencing the risk and age at onset of Alzheimer's disease. PMID: 28778446
  3. interaction between NAV2 and 14-3-3epsilon PMID: 24161943
  4. regulated by all-trans retinoic acid in neuroblastoma cells PMID: 11904404
  5. a novel gene, termed HELAD1 (helicase, APC down-regulated 1) plays important role in colorectal carcinogenesis (HELAD1) PMID: 12214280

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Subcellular Location
Nucleus.
Protein Families
Nav/unc-53 family
Tissue Specificity
Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.
Database Links

HGNC: 15997

OMIM: 607026

KEGG: hsa:89797

STRING: 9606.ENSP00000379394

UniGene: Hs.502116

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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