NMD3 Antibody

Code CSB-PA836194XA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NMD3 Polyclonal antibody
Uniprot No.
Target Names
NMD3
Alternative Names
60S ribosomal export protein NMD3 antibody; CGI 07 antibody; FLJ21053 antibody; hNMD3 antibody; NMD3 antibody; NMD3 homolog antibody; NMD3 homolog (S. cerevisiae) antibody; NMD3 ribosome export adaptor antibody; NMD3, S. cerevisiae, homolog of antibody; NMD3_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens (Human)
Immunogen
Recombinant Homo sapiens (Human) NMD3 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
Gene References into Functions
  1. The presence of the rs34016896 allele in the NMD3 gene may contribute to the development of synucleinopathies. PMID: 29564728
  2. The CRM1 and NMD3 have complex functions in pathways that couple rRNA synthetic and processing engines and that the rRNA synthesis rate may be adjusted according to proficiency in rRNA processing and export. PMID: 23782956
  3. contains a CRM-1-dependent leucine-rich nuclear export signal and a complex, dispersed nuclear localization signal (NMD3) PMID: 12773398
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
NMD3 family
Database Links

HGNC: 24250

OMIM: 611021

KEGG: hsa:51068

STRING: 9606.ENSP00000307525

UniGene: Hs.598836

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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