NPC1 Antibody

Code CSB-PA619571XA01SVG
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Product Details

Full Product Name Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) NCR1 Polyclonal antibody
Uniprot No. Q12200
Target Names NCR1
Alternative Names NCR1 antibody; YPL006W antibody; NPC intracellular sterol transporter 1-related protein 1 antibody; Niemann-Pick type C-related protein 1 antibody
Raised in Rabbit
Species Reactivity Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) NPC1 protein
Immunogen Species Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Made-to-order

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Target Data

Function Involved in sphingolipid trafficking. May recycle sphingolipids between cellular membranous compartments.
Gene References into Functions
  1. Authors show that yeast cells lacking Ncr1p, an orthologue of mammalian NPC1, exhibited a higher sensitivity to hydrogen peroxide and a shortened chronological lifespan. PMID: 24286211
  2. Results identify the first phenotype caused by deletion of NCR1 from the yeast genome, resistance to the ether lipid drug, edelfosine. PMID: 16138904
Subcellular Location Vacuole membrane, Multi-pass membrane protein
Protein Families Patched family
Database Links

KEGG: sce:YPL006W

STRING: 4932.YPL006W

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