Nrg Antibody

1. Neuroglian mediates adhesion between functionally distinct mushroom body axon populations to enforce and control appropriate projections into distinct axonal layers and lobes essential for olfactory learning and memory. PMID: 25825519
2. Nrg plays a critical inhibitory role in dendrite pruning in dendritic arborization neurons. PMID: 25158855
3. Regulation of the interaction between Neuroglian and Ankyrin is an important novel module enabling local control of synaptic connectivity and function. PMID: 23610557
4. Data describe the role of the L1-type CAM Neuroglian protein (NRG) in different steps of Drosophila mushroom body (MB) neuron axonogenesis. PMID: 21389050
5. results suggest a model in which Nrg acts as a heterophilic ligand and activator of echinoid, which in turn antagonizes EGFR signaling PMID: 12668620
6. Neuroglian stabilizes epithelial structure during Drosophila oogenesis PMID: 15254915
7. Resutls show the ibx mutation maps to the 7F region of the Drosophila X chromosome to form a complex complementation group with both lethal and viable alleles of neuroglian (nrg). PMID: 16268990
8. Nrg has a function in synapse formation by organizing microtubules in the synaptic terminal. PMID: 16401420
9. Neuroglian is necessary to maintain axon advance along axonal substrates, but is not required for initiation of axon outgrowth, axon fasciculation or recognition of correct growth substrates PMID: 18397531
10. Data show that Neuroglian (Nrg), the Drosophila homolog of the vertebrate cell adhesion molecule, L1, is expressed and functions in the midline glial cells to regulate their proper development. PMID: 18446783
11. Data show that the lateral mobility of cell adhesion molecules neurexin IV, neuroglian, and contactin is highly restricted at septate junctions in Drosophila. PMID: 18638384
12. Neuroglian regulates the localisation of the nucleokinesis complex protein lissencephaly-1. PMID: 19320973

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KEGG: dme:Dmel_CG1634

STRING: 7227.FBpp0297081

UniGene: Dm.3700