NTHL1 Antibody

Code CSB-PA108707XA01CH
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Product Details

Full Product Name
Rabbit anti-Gallus gallus (Chicken) NTHL1 Polyclonal antibody
Uniprot No.
Target Names
NTHL1
Alternative Names
NTHL1Endonuclease III-like protein 1 antibody; EC 3.2.2.- antibody; EC 4.2.99.18 antibody; Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase antibody; DNA glycosylase/AP lyase antibody
Raised in
Rabbit
Species Reactivity
Gallus gallus (Chicken)
Immunogen
Recombinant Gallus gallus (Chicken) NTHL1 protein
Immunogen Species
Gallus gallus (Chicken)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
Subcellular Location
Nucleus. Mitochondrion.
Protein Families
Nth/MutY family
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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