ORC3 Antibody

Code CSB-PA866199XA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ORC3 Polyclonal antibody
Uniprot No.
Target Names
ORC3
Alternative Names
Homolog of Latheo antibody; homolog of latheo, Drosophila antibody; LAT antibody; LATHEO antibody; LATHEO, drosophila, homolog of antibody; orc3 antibody; ORC3_HUMAN antibody; ORC3L antibody; Origin recognition complex subunit 3 antibody; Origin recognition complex subunit 3 honolog antibody; Origin Recognition Complex Subunit 3 Isoform 1 antibody; Origin recognition complex subunit 3 like antibody; Origin recognition complex subunit Latheo antibody; Origin Recognition Complex, subunit 3, S. cerevisiae, homolog of antibody; Origin recognition complex, subunit 3-like (S. cerevisiae) antibody; Origin recognition complex, subunit 3-like (yeast) antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens (Human)
Immunogen
Recombinant Homo sapiens (Human) ORC3 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.
Gene References into Functions
  1. Lifetime severity of positive symptoms was significantly (P = 2.50 x 10(-5)) associated with a SNP within the origin recognition complex subunit 3-like (ORC3L) gene, a gene implicated in synaptic plasticity. PMID: 18628273
Subcellular Location
Nucleus. Chromosome.
Protein Families
ORC3 family
Database Links

HGNC: 8489

OMIM: 604972

KEGG: hsa:23595

STRING: 9606.ENSP00000257789

UniGene: Hs.410228

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA
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