PCNA Antibody

Code CSB-PA017621XA01DLU
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Product Details

Full Product Name Rabbit anti-Drosophila melanogaster (Fruit fly) PCNA Polyclonal antibody
Uniprot No. P17917
Target Names PCNA
Alternative Names PCNA antibody; mus209 antibody; PCNA1 antibody; CG9193 antibody; Proliferating cell nuclear antigen antibody; PCNA antibody; Cyclin antibody; Mutagen-sensitive 209 protein antibody
Raised in Rabbit
Species Reactivity Drosophila melanogaster (Fruit fly)
Immunogen Recombinant Drosophila melanogaster (Fruit fly) PCNA protein
Immunogen Species Drosophila melanogaster (Fruit fly)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Made-to-order

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Target Data

Function This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
Gene References into Functions
  1. crystal of DmPCNA diffracted to 2.0 A resolution and belonged to space group H3, with unit-cell parameters a = b = 151.16, c = 38.28 A PMID: 23545643
  2. We observed that SUUR chromosomal localization changed along with PCNA pattern and these proteins largely co-localized during the late S-phase in salivary glands. PMID: 23149855
  3. E2F regulation of PCNA is dispensable for viability, but is nonetheless important for normal Drosophila development. PMID: 12526745
  4. A Q123V mutation dramaticly enhances the abilities of Drosophila PCNA to stimulate calf thymus pol delta. Replacing the entire interdomain connector loop AA 119-133 with the corresponding residues from human PCNA results in additional enhancement. PMID: 15310391
Subcellular Location Nucleus
Protein Families PCNA family
Tissue Specificity Expressed at high levels in adult ovary.
Database Links

KEGG: dme:Dmel_CG9193

STRING: 7227.FBpp0085619

UniGene: Dm.4751

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