pde-4 Antibody

Datasheet

Code	CSB-PA638717XA01CXY
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Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans pde-4 Polyclonal antibody

Uniprot No.

Q22000

Target Names

pde-4

Alternative Names

pde-4 antibody; R153.1 antibody; Probable 3',5'-cyclic phosphodiesterase pde-4 antibody; EC 3.1.4.17 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans pde-4 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Antagonizes dorsal D (DD) motor neuron respecification by reducing levels of cAMP.

Gene References into Functions

Loss of function and neural overexpression of PDE-4 have profound and opposite effects on locomotion rate, but drug-response assays suggest that loss of PDE-4 function does not affect steady-state acetylcholine release or reception. PMID: 16624912

Protein Families

Cyclic nucleotide phosphodiesterase family

Tissue Specificity

Expressed in dorsal D (DD) motor neurons and several other neurons at the L1 stage. Expression in DD neurons decreases gradually beginning in the late L1 stage. Highly expressed in adult ventral D (VD) motor neurons, but diminished in adult DD motor neuro

Database Links

STRING: 6239.R153.1d

UniGene: Cel.17824

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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pde-4 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background