rush Antibody

Code CSB-PA447717XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) rush Polyclonal antibody
Uniprot No.
Target Names
rush
Alternative Names
rush antibody; EG:80H7.5 antibody; CG14782 antibody; Pleckstrin homology domain-containing family F member 1 homolog antibody; PH domain-containing family F member 1 homolog antibody; Protein rush hour antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) rush protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Functions in the regulation of endosome morphology and late endosome formation. Has a role in controlling trafficking from early to late endosomes and from late endosomes to lysosomes. Important for localization of Gdi to the endosomal membranes. May function in controlling the activity of multiple regulators in the endocytic pathway, perhaps by positively controlling those involved in the early steps of endocytosis such as Rab5 and hrs, and negative regulating those involved in the late stages of endocytosis like car and VhaSFD.
Gene References into Functions
  1. Rush controls trafficking from early to late endosomes and from late endosomes to lysosomes by modulating the activity of Rab proteins. PMID: 22160599
Subcellular Location
Apical cell membrane. Endosome membrane. Cytoplasm, cell cortex.
Tissue Specificity
In ovaries, expressed both in the germ line cells and in the overlying somatic follicular epithelium.
Database Links

KEGG: dme:Dmel_CG14782

STRING: 7227.FBpp0070249

UniGene: Dm.7010

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