pnp Antibody

1. Inhibition of homologous PNPase by citrate may represent an evolutionarily conserved communicative link between RNA degradation and central metabolism. PMID: 28334892
2. PNPase and RNase PH facilitate the stability and regulatory function of the sRNAs RyhB, CyaR, and MicA during exponential growth. PMID: 27698082
3. A conserved loop in polynucleotide phosphorylase (PNPase) is essential for both RNA and ADP/phosphate binding. PMID: 24075876
4. These results demonstrate that polynucleotide phosphorylase is necessary to maintain bacterial cells in the planktonic mode through down-regulation of pgaABCD expression and PNAG production. PMID: 23171129
5. S1 and KH domains of pnp determine the efficiency of RNA binding and autoregulation. PMID: 23457244
6. Spontaneous mutations resulting from replication errors, which are normally repaired by the mismatch repair (MMR) system, are sharply reduced in a polynucleotide phosphorylase-deficient Escherichia coli strain. PMID: 22904280
7. Absence of PNPase decreases the survival of cells exposed to UV radiation. PMID: 22322961
8. Role of polynucleotide phosphorylase in sRNA function in Escherichia coli PMID: 21527671
9. Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli PMID: 21324911
10. examined roles of the conserved S1 and KH RNA binding motifs in PNPase; propose that the S1 domain, possibly arrayed with the KH domain, forms an RNA binding surface that facilitates substrate recognition and thus indirectly potentiates product release PMID: 16237005
11. results indicate that two clones of PNPase including residues 158-262 and residues 473-577 contain interaction sites for RNase E within a betabetaalphabetabetaalpha domain configuration PMID: 16483707
12. suppression of Rho-dependent transcription termination within pnp and its restoration by PNPase is an autogenous regulatory circuit that modulates pnp expression during cold acclimation PMID: 17384964
13. new role for PNPase in the degradation of small noncoding RNAs PMID: 18203924
14. The constricted central channel and the basic-charged residues in the channel necks of PNPase play crucial roles in trapping RNA for processive exonucleolytic degradation. PMID: 18812438
15. Translational control by PNPase does not play a role in autoregulation of PNP RNA. PMID: 19136586
16. Data show that introducing the pnp gene encoding PNPase rescues defects in growth and RNA quality of the pnp mutant cells. PMID: 19219992

Show More

Hide All

KEGG: ecj:JW5851

STRING: 316385.ECDH10B_3337