PS/HR Antibody

Code CSB-PA312446ZA01VAI
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Product Details

Full Product Name
Rabbit anti-Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) PS/HR Polyclonal antibody
Uniprot No.
Target Names
PS/HR
Alternative Names
PS/HR antibody; VACWR187 antibody; B5RProtein B5 antibody; Plaque-size/host range protein antibody
Raised in
Rabbit
Species Reactivity
Vaccinia virus
Immunogen
Recombinant Vaccinia virus PS/HR protein
Immunogen Species
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV).
Gene References into Functions
  1. Tanslation of vaccinia virus A27L and B5R genes is independent of PKR activation, but their expression is dependent on the RNase L activity. PMID: 26656695
  2. These results suggest that in the absence of A33, the cytoplasmic tail of B5 contributes to its incorporation into the envelope of progeny virions. PMID: 20378144
Subcellular Location
Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus, host trans-Golgi network. Note=B5 is found on enveloped virion (EV) membranes.
Protein Families
Receptors of complement activation (RCA) family
Database Links

KEGG: vg:3707658

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