PS/HR Antibody

Code CSB-PA312446ZA01VAI
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Product Details

Full Product Name Rabbit anti-Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) PS/HR Polyclonal antibody
Uniprot No. Q01227
Target Names PS/HR
Alternative Names PS/HR antibody; VACWR187 antibody; B5RProtein B5 antibody; Plaque-size/host range protein antibody
Raised in Rabbit
Species Reactivity Vaccinia virus
Immunogen Recombinant Vaccinia virus PS/HR protein
Immunogen Species Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (12-14 weeks)

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Target Background

(From Uniprot)
Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV).
Gene References into Functions
  1. Tanslation of vaccinia virus A27L and B5R genes is independent of PKR activation, but their expression is dependent on the RNase L activity. PMID: 26656695
  2. These results suggest that in the absence of A33, the cytoplasmic tail of B5 contributes to its incorporation into the envelope of progeny virions. PMID: 20378144
Subcellular Location Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus, host trans-Golgi network. Note=B5 is found on enveloped virion (EV) membranes.
Protein Families Receptors of complement activation (RCA) family
Database Links

KEGG: vg:3707658

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