RAD16 Antibody

Code CSB-PA341214XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RAD16 Polyclonal antibody
Uniprot No.
Target Names
RAD16
Alternative Names
RAD16 antibody; YBR114W antibody; YBR0909 antibody; DNA repair protein RAD16 antibody; EC 3.6.4.- antibody; ATP-dependent helicase RAD16 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RAD16 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the global genome repair (GGR) complex which promotes global genome nucleotide excision repair (GG-NER) which removes DNA damage from nontranscribing DNA. Involved in differential repair of DNA after UV damage. Will repair preferentially the MAT-alpha locus compared with the HML-alpha locus.
Gene References into Functions
  1. Rad16 is solely responsible for repairing the nontranscribed strand of actively transcribed genes PMID: 17611170
  2. Rad16 mediates the ultraviolet-induced acetylation of histone H3, necessary for efficient global genome nucleotide-excision repair. PMID: 18007656
  3. use of rad7 Delta rad16 Delta mutants showed that Rad7-Rad16 is required for nucleotide excision repair of UV-lesions in three functionally distinct nucleosome-free regions, the promoter and 3'-end of the URA3 gene and the ARS1 origin of replication PMID: 18329964
Subcellular Location
Nucleus.
Protein Families
SNF2/RAD54 helicase family
Database Links

KEGG: sce:YBR114W

STRING: 4932.YBR114W

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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