rev Antibody

Code CSB-PA319405XA01HMA
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Product Details

Full Product Name Rabbit anti-Human immunodeficiency virus type 2 subtype A (isolate SBLISY) (HIV-2) rev Polyclonal antibody
Uniprot No. P12448
Target Names rev
Alternative Names rev antibody; Protein Rev antibody; Regulator of expression of viral proteins antibody
Raised in Rabbit
Species Reactivity Human immunodeficiency virus type 2 subtype A (isolate SBLISY) (HIV-2)
Immunogen Recombinant Human immunodeficiency virus type 2 subtype A (isolate SBLISY) (HIV-2) rev protein
Immunogen Species Human immunodeficiency virus type 2 subtype A (isolate SBLISY) (HIV-2)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

Function
(From Uniprot)
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.
Subcellular Location Host nucleus, host nucleolus. Host cytoplasm.
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