RHO5 Antibody

Code CSB-PA347442XA01SVG
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Product Details

Full Product Name Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RHO5 Polyclonal antibody
Uniprot No. P53879
Target Names RHO5
Alternative Names RHO5 antibody; YNL180C antibody; N1644 antibody; GTP-binding protein RHO5 antibody
Raised in Rabbit
Species Reactivity Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RHO5 protein
Immunogen Species Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

(From Uniprot)
Small GTPase that negatively regulates a MAP kinase branch, downstream of SLT2, of the PKC1-mediated signal transduction pathway. With its specific guanine nucleotide exchange factor (GEF), the heterodimeric complex DCK1/LMO1, relocates to mitochondria upon oxidative stress and triggers cell death. The DCK1/LMO1/RHO5 signaling module that mediates mitochondrial turnover under nitrogen starvation conditions via mitophagy. The DCK1/LMO1/RHO5 signaling module plays also a function in cell wall integrity signaling.
Gene References into Functions
  1. Rho5 mediates H(2)O(2)-induced cell death by regulating the level of Trr1 or by excluding Trr1 from its cytoplasmic substrate. PMID: 18216266
Subcellular Location Membrane; Lipid-anchor. Mitochondrion.
Protein Families Small GTPase superfamily, Rho family
Database Links

KEGG: sce:YNL180C

STRING: 4932.YNL180C

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