RIN4 Antibody

1. Bacterial effector AvrB-induced RPM1 interacting protein 4 (RIN4) phosphorylation depends on receptor-like cytoplasmic kinase (RLCK) in Arabidopsis. PMID: 28353399
2. Transiently expressed RIN4, but not the plasma membrane (PM) protein aquaporin PIP2, recruits EXO70B1 to the plasma membrane (PM). Unlike EXO70B1, RIN4 does not recruit the core exocyst subunit SEC6 to the PM under these conditions. PMID: 28338727
3. RIN4 is intrinsically disordered and it's AvrRpt2 cleavage sites coincide with Molecular Recognition Features (MoRFs) that typically direct protein-protein interaction within other disordered proteins. PMID: 25039985
4. Consistent with this, RIN4 Pro149 undergoes cis/trans isomerization in the presence of ROC1. PMID: 25299333
5. Authors demonstrate that recognition of the flagellin peptide microbe-associated molecular pattern flg22 triggers accumulation of RIN4 phosphorylated at serine 141 (pS141) that mediates derepression of several immune outputs. PMID: 25299334
6. RIN4 is a multifunctional suppressor of PTI and that a virulence function of AvrRpt2 may include cleaving RIN4 into active defense-suppressing fragments. PMID: 21984695
7. Pseudomonas syringae virulence activity was not observed in plants genetically lacking RIN4. PMID: 20133879
8. These results indicate that the virulence activity of AvrRpt2 in Arabidopsis thaliana is likely to rely on the modification of host susceptibility factors other than, or in addition to, RIN4. PMID: 15546361
9. In addition to characterizing the RPS2-RIN4 association in N. benthamiana, we have moved forward to show that the biological relevance of these amino acid changes is applicable in Arabidopsis as well. PMID: 15749765
10. RIN4 was attached to the plasma membrane at its carboxyl terminus; RIN4 was cleaved by AvrRpt2 at two PxFGxW motifs. PMID: 16478045
11. Multiple bacterial effectors besides AvrRpt2 elicit proteolysis of RIN4 in planta. PMID: 19671880

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KEGG: ath:AT3G25070

STRING: 3702.AT3G25070.1

UniGene: At.43082