SP1 Antibody

Datasheet

Code	CSB-PA973357XA01DOA
Size	Enquire
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SP1 Polyclonal antibody

Uniprot No.

Q8L7N4

Target Names

SP1

Alternative Names

SP1 antibody; DIAL1 antibody; At1g63900/At1g63890 antibody; T12P18.8/T12P18.9 antibody; E3 ubiquitin-protein ligase SP1 antibody; EC 2.3.2.27 antibody; DIAP1-like protein 1 antibody; Protein SUPPRESSOR OF PPI1 LOCUS 1 antibody; RING-type E3 ubiquitin transferase SP1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana SP1 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

E3 ubiquitin-protein ligase involved in the regulation of protein import in the chloroplast. Associates with TOC complexes and mediates ubiquitination of TOC components, promoting their degradation via the ubiquitin-proteasome system (UPS). Plays a role in the reorganization of the TOC machinery. Involved in a mechanism that regulates plastid biogenesis via UPS. Promotes stress tolerance by depleting the chloroplast protein import apparatus, which limits photosystem assembly and the potential for reactive oxygen species (ROS) formation. May act as negative regulator of programmed cell death (PCD) during biotic stress.

Gene References into Functions

In this study, we identified the Arabidopsis RING-type E3 ubiquitin ligase SP1 as a peroxisome membrane protein that regulates peroxisome biogenesis. PMID: 27799549
SP1 protein (At1g63900) associated with TOC (translocon at the outer envelope of chloroplasts) complexes and mediated ubiquitination of TOC components, promoting degradation; mutant sp1 plants performed developmental transitions involving plastid proteome changes inefficiently, indicating requirement for reorganization of TOC machinery PMID: 23118188

Subcellular Location

Plastid, chloroplast outer membrane; Multi-pass membrane protein.

Database Links

KEGG: ath:AT1G63900

UniGene: At.22411

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

An Overview of Cell Death: Necrosis and Apoptosis CLDN6: A "New Favorite" in Targeted Cancer Therapy after CLDN 18.2! CD14, A Membrane Receptor for Bacterial Lipopolysaccharides Exploring Biological Landscape of Cervical Cancer: A Comprehensive Overview for Researchers CLDN4: A Potential Prognostic Indicator and Therapeutic Target in Tumors！ Protein Phosphorylation: The Dynamic Language of Cellular Regulation ULBP1: a Potent Member of NKG2D Ligands in CAR-T Therapy for Multiple Hematological and Solid Tumors! Oct4 -- The Gatekeeper of Pluripotency of Embryonic Stem Cells ACVRL1 (Alk1): a Member of the TGF-β Receptor Family, a Novel Target for Anti-Angiogenic Drug Research! CD47, A New Target for Tumor Immune CD20 Monoclonal Antibodies Drugs: There is an Explosion of New mAbs Against CD20! What You Have To Know about Lung Cancer CD146, A Powerful Tumor Marker SIGIRR: A Novel Member of the TIR Superfamily Acts as the Anti-Inflammatory 'Brake' to Control Immune Response in Various Diseases! Tetraspanin CD81: a Key Receptor for Hepatitis C Virus (HCV), an Established Exosome Marker, a Promising Target for Antiviral or Antitumor Research! TMPRSS2, an Activator for SARS-CoV-2 Invasion TM4SF1: a Member of the Transmembrane-4-Superfamily (L6), a New Vascular Therapeutic Target? Exploring the Science of Influenza A Virus: What You Need to Know The Overview of Interleukin Dipeptidase 3 (DPEP3): an Emerging Member of the DPEP Family, a Potential Therapeutic Target in Male Fertility or Tumor Research! Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Estrogen signaling pathway TGF-beta signaling pathway Mitophagy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：