SP1

Transcription factor Sp1is a protein in humans that is encoded by SP1 gene. Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

SP1 Antibodies

SP1 Antibodies for Homo sapiens (Human)

SP1 Proteins

SP1 Proteins for Homo sapiens (Human)

SP1 Proteins for Mus musculus (Mouse)

SP1 ELISA Kit

SP1 ELISA Kit for Homo sapiens (Human)

SP1 ELISA Kit for Mus musculus (Mouse)

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