Transcription factor Sp1is a protein in humans that is encoded by SP1 gene. Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
The following SP1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SP1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA022438GA01HU | SP1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA730012 | Phospho-SP1 (Thr739) Antibody |
Human,Rat | ELISA,WB |
CSB-PA000619 | Phospho-SP1 (T739) Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA050123 | Phospho-SP1 (T453) Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA050124 | SP1 Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA671453 | SP1 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA620368 | SP1 Antibody |
Human,Mouse,Rat | ELISA,IHC |
SP1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA973357XA01DOA | SP1 Antibody |
Arabidopsis thaliana | ELISA, WB (ensure identification of antigen) |
SP1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP022438HU CSB-EP022438HU CSB-BP022438HU CSB-MP022438HU CSB-EP022438HU-B |
Recombinant Human Transcription factor Sp1 (SP1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SP1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP022438MO CSB-EP022438MO CSB-BP022438MO CSB-MP022438MO CSB-EP022438MO-B |
Recombinant Mouse Transcription factor Sp1 (Sp1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SP1 Proteins for BOMMO(Silk moth)
Code | Product Name | Source |
---|---|---|
CSB-YP357592BTT CSB-EP357592BTT CSB-BP357592BTT CSB-MP357592BTT CSB-EP357592BTT-B |
Recombinant Bombyx mori Sex-specific storage-protein 1 (SP1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |