spd-5 Antibody

Code CSB-PA308592XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans spd-5 Polyclonal antibody
Uniprot No.
Target Names
spd-5
Alternative Names
spd-5 antibody; F56A3.4 antibody; Spindle-defective protein 5 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans spd-5 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a central role in centrosome maturation and mitotic spindle assembly during the first division of the zygote. Required for the centrosomal localization of air-1 and zyg-9. Probably not required in late embryogenesis and during larval development.
Gene References into Functions
  1. Recruitment of the scaffold component SPD-5 occurs throughout the pericentriolar material (PCM). Incorporation of additional PCM subunits is therefore not limited to specific nucleation sites near centrioles. PMID: 26241136
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Database Links

KEGG: cel:CELE_F56A3.4

STRING: 6239.F56A3.4

UniGene: Cel.5774

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