STRN3 Antibody

Code CSB-PA614388ZA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) STRN3 Polyclonal antibody
Uniprot No.
Target Names
STRN3
Alternative Names
Striatin-3 (Cell cycle autoantigen SG2NA) (S/G2 antigen), STRN3, GS2NA SG2NA
Raised in
Rabbit
Species Reactivity
Homo sapiens
Immunogen
Recombinant Homo sapiens STRN3 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugate
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
Gene References into Functions
  1. this study propose that the STRIPAK complex, FAM40A, FAM40B and STRN3, regulates the mode of cancer cell migration by controlling the activity of MST3 and 4, which locally coordinate the phosphorylation of ERM proteins and inhibit the dephosphorylation of MLC leading to increased actin-membrane linkage. PMID: 25531779
  2. The structure and protein-binding domains of the SG2NA protein variants have been described. PMID: 25015106
  3. This result combined with a number of biophysical analyses provide evidence that the coiled coil domain of striatin 3 and the PP2A A subunit form a stable core complex with a 2:2 stoichiometry PMID: 24550388
  4. STRN3 (rs2273171)is associated with single nucleotide polymorphisms in Korean patients, either non-segmental or segmental type. PMID: 23678272
Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein.
Protein Families
WD repeat striatin family
Database Links

HGNC: 15720

OMIM: 614766

KEGG: hsa:29966

STRING: 9606.ENSP00000350071

UniGene: Hs.401843

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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