su(sable) Antibody

Code CSB-PA325265XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) su(sable) Polyclonal antibody
Uniprot No.
Target Names
su(sable)
Alternative Names
su(sable) antibody; su(s) antibody; CG6222 antibody; Protein suppressor of sable antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) su(sable) protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Affects the transcript levels of those alleles that it suppresses. May be involved in influencing complex assembly on cryptic 5'-splice sites or nuclear RNA export; binds RNA preferentially at a sequence that resembles a cryptic 5'-splice site (in vitro).
Gene References into Functions
  1. identify Wdr82 as a component of this process and show that it works with Su(s) to inhibit Pol II elongation through Hsp70-alphabeta elements PMID: 26577379
  2. results reveal a link between suppressor of sable, transcription, and pre-mRNA processing PMID: 15082769
  3. Su(s) binds to certain nascent transcripts and stimulates their degradation by the nuclear exosome. PMID: 19687295
Subcellular Location
Nucleus. Note=Distributed in a reticulated pattern in embryo and salivary gland.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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