ttk Antibody

Code CSB-PA804301XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) ttk Polyclonal antibody
Uniprot No.
Target Names
ttk
Alternative Names
ttk antibody; mps1 antibody; ncp antibody; Dual specificity protein kinase Ttk antibody; EC 2.7.12.1 antibody; Mitotic checkpoint serine/threonine-protein kinase Mps1 antibody; Monopolar spindle protein 1 antibody; Protein nightcap antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) ttk protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Phosphorylates proteins on serine, threonine, and tyrosine. Involved in mitotic cell cycle checkpoint control. Required for fin and heart regeneration. Required to prevent chromosome segregation errors during meiosis.
Gene References into Functions
  1. the proximal blastema comprises an essential subpopulation of the fin regenerate defined by the induction and function of Mps1 PMID: 12399306
  2. Mps1 is a critical regulator of chromosome number in zebrafish PMID: 15231734
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Tissue Specificity
Barely detectable in adult somatic tissues. Expressed in immature germ cells that have not completed meiosis. In ovary, expressed predominantly in previtellogenic oocytes. In testis, expressed in primary and secondary spermatocytes, but not mature spermat
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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