Unc13b Antibody

Datasheet

Code	CSB-PA714031XA01RA
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Product Details

Full Product Name

Rabbit anti-Rattus norvegicus (Rat) Unc13b Polyclonal antibody

Uniprot No.

Q62769

Target Names

Unc13b

Alternative Names

Unc13b antibody; Unc13h2Protein unc-13 homolog B antibody; Munc13-2 antibody

Raised in

Rabbit

Species Reactivity

Rattus norvegicus (Rat)

Immunogen

Recombinant Rattus norvegicus (Rat) Unc13b protein

Immunogen Species

Rattus norvegicus (Rat)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. In collaboration with UNC13A, facilitates neuronal dense core vesicles fusion as well as controls the location and efficiency of their synaptic release.

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein. Cell membrane. Cell junction, synapse. Note=Localized to synapses. Translocated to the plasma membrane in response to phorbol ester binding.

Protein Families

Unc-13 family

Tissue Specificity

Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain, predominantly in cerebral cortex, hippocampus and striatum.

Database Links

KEGG: rno:64830

STRING: 10116.ENSRNOP00000058802

UniGene: Rn.10127

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Excitatory synapse pathway Synaptic vesicle cycle

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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Unc13b Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background