Upk3a Antibody

Datasheet

Code	CSB-PA862403ZA01MO
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Product Details

Full Product Name

Rabbit anti-Mus musculus (Mouse) Upk3a Polyclonal antibody

Uniprot No.

Q9JKX8

Target Names

Upk3a

Alternative Names

Upk3a antibody; Upk3 antibody; Uroplakin-3a antibody; UP3a antibody; Uroplakin III antibody; UPIII antibody

Raised in

Rabbit

Species Reactivity

Mus musculus

Immunogen

Recombinant Mus musculus Upk3a protein

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (12-14 weeks)

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Target Background

Function

Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.

Gene References into Functions

U-CCs (Uroplakin3a expressing cells )proliferate and generate CCs and ciliated cells in uninjured airways long-term and, like v-CCs, after Nap. U-CCs have a higher propensity to generate ciliated cells than non-U-CCs PMID: 28402849
A UPK3A peptide can induce a peptide-specific CD4+ T cell autoimmunity that mediates painful bladder dysfunction in mice. PMID: 23977210
The despites a lower level of expression, UPIIIa maintain its plaque association in urothelial preneoplastic lesions. PMID: 21853341

Subcellular Location

Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Protein Families

Uroplakin-3 family

Database Links

KEGG: mmu:22270

STRING: 10090.ENSMUSP00000023070

UniGene: Mm.46214

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Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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Upk3a Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background