Urah Antibody

Code CSB-PA863439ZA01MO
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Product Details

Full Product Name Rabbit anti-Mus musculus (Mouse) Urah Polyclonal antibody
Uniprot No. Q9CRB3
Target Names Urah
Alternative Names Urah5-hydroxyisourate hydrolase antibody; HIU hydrolase antibody; HIUHase antibody; EC 3.5.2.17 antibody; Transthyretin-related protein antibody
Raised in Rabbit
Species Reactivity Mus musculus
Immunogen Recombinant Mouse 5-hydroxyisourate hydrolase (Urah) (1-118AA)
Immunogen Species Mus musculus (Mouse)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Made-to-order

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Target Data

Function Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
Gene References into Functions
  1. Substitution of cysteine for tyrosine in a conserved helical region of HIU hydrolase resulted in undetectable protein expression. Homozygotes for the mutation had elevated platelet counts secondary to excess thrombopoietin production and hepatomegaly. PMID: 20823251
  2. Study provides evidence that mouse transthyretin-related protein facilitates the hydrolysis of 5-hydroxyisourate, the end product of the uricase reaction. PMID: 17085964
  3. Identified as the gene encoding the enzyme catalyzing the second step of the pathway from uric acid to S-allantoin. PMID: 16462750
Subcellular Location Peroxisome
Protein Families Transthyretin family, 5-hydroxyisourate hydrolase subfamily
Database Links

KEGG: mmu:76974

STRING: 10090.ENSMUSP00000026554

UniGene: Mm.272359

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