ZNF638 Antibody

Code CSB-PA026909ZA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZNF638 Polyclonal antibody
Uniprot No.
Target Names
ZNF638
Alternative Names
CTCL tumor antigen se33 1 antibody; CTCL-associated antigen se33-1 antibody; Cutaneous T cell lymphoma associated antigen se33 1 antibody; Cutaneous T-cell lymphoma-associated antigen se33-1 antibody; DKFZp686P1231 antibody; MGC26130 antibody; MGC90196 antibody; NP220 antibody; NP220 nuclear protein antibody; Nuclear protein 220 antibody; ZFML antibody; Zfp638 antibody; Zinc finger matrin like antibody; Zinc finger matrin like protein antibody; Zinc finger matrin-like protein antibody; Zinc finger protein 638 antibody; ZN638_HUMAN antibody; ZNF 638 antibody; Znf638 antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens
Immunogen
Recombinant Homo sapiens ZNF638 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Transcription factor that binds to cytidine clusters in double-stranded DNA. Plays a key role in the silencing of unintegrated retroviral DNA: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed. Mediates transcriptional repression of unintegrated viral DNA by specifically binding to the cytidine clusters of retroviral DNA and mediating the recruitment of chromatin silencers, such as the HUSH complex, SETDB1 and the histone deacetylases HDAC1 and HDAC4. Acts as an early regulator of adipogenesis by acting as a transcription cofactor of CEBPs (CEBPA, CEBPD and/or CEBPG), controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1. May also regulate alternative splicing of target genes during adipogenesis.
Gene References into Functions
  1. ZNF638 is a novel and early regulator of adipogenesis that works as a transcription cofactor of C/EBPs. PMID: 21602272
Subcellular Location
Nucleus speckle.
Database Links

HGNC: 17894

OMIM: 614349

KEGG: hsa:27332

STRING: 9606.ENSP00000264447

UniGene: Hs.434401

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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