dda Antibody

Code CSB-PA329153ZA01EDZ
Size
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Enterobacteria phage T4 (Bacteriophage T4) dda Polyclonal antibody
Uniprot No.
Target Names
dda
Alternative Names
ATP-dependent DNA helicase dda (EC 3.6.4.12), dda, sud
Raised in
Rabbit
Species Reactivity
Enterobacteria phage T4
Immunogen
Recombinant Enterobacteria phage T4 dda protein
Immunogen Species
Enterobacteria phage T4 (Bacteriophage T4)
Conjugate
Non-conjugate
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
DNA helicase that stimulates viral DNA replication and recombination. Plays a role in T4 DNA replication initiation by selecting and activating DNA origins. Acts by dissociating and reassociating with the DNA molecule being unwound. Unwinds DNA as a monomer in a 5'-to-3' direction at a rate of 250 bp/s and can efficiently displace proteins from the DNA.
Gene References into Functions
  1. Gp32 plays both positive and negative roles in regulating Dda helicase activity, and that both effects may influence the outcome of complex DNA transactions such as replication fork restart. PMID: 25481875
  2. Dda cross-links to DNA in the 167-199 Peptide. PMID: 19256528
  3. Dda suffice to rescue stalled T4 replication forks in vitro PMID: 15194689
  4. Enhanced binding to the longer single-stranded overhangs was not responsible for enhanced processivity under conditions of excess Dda enzyme. Rather, multiple molecules of Dda bound to the same substrate exhibit greater processivity for DNA unwinding. PMID: 16185067
  5. observations demonstrate a complex mechanism containing nonuniform steps for a monomeric helicase PMID: 16474403
  6. Multiple Dda molecules act to displace DNA binding proteins in a manner that correlates with the DNA unwinding activity and streptavidin displacement activity. PMID: 16738140

Show More

Hide All

Database Links

KEGG: vg:1258784

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1