Human Angiopoietin 2,ANG-2 ELISA Kit

Instructions
Code CSB-E04500h
Size 96T,5×96T,10×96T
See More Details 24T ELISA kits trial application

Product Details

Target Name angiopoietin 2
Alternative Names AGPT2, ANG2, Tie2-ligand|angiopoietin-2|angiopoietin-2B|angiopoietin-2a
Abbreviation ANGPT2
Uniprot No. O15123
Species Homo sapiens (Human)
Sample Types serum, plasma, tissue homogenates
Detection Range 39 pg/mL-2500 pg/mL
Sensitivity 9.75 pg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Cardiovascular
Assay Principle quantitative
Measurement Sandwich
Precision
Linearity
Recovery
Typical Data
Troubleshooting
and FAQs
ELISA kit FAQs
Storage Store at 2-8°C. Please refer to protocol.
Lead Time 3-5 working days
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Target Data

Function Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Subcellular Location Secreted
Database Links

HGNC: 485

OMIM: 601922

KEGG: hsa:285

STRING: 9606.ENSP00000314897

UniGene: Hs.583870

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