Human Growth hormone variant(GH2) ELISA kit

Code CSB-EL009408HU
Size 96T,5×96T,10×96T
Price Request a Quote or Start an on-line Chat
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Alternative Names
GH2 ELISA Kit; Growth hormone variant ELISA Kit; GH-V ELISA Kit; Growth hormone 2 ELISA Kit; Placenta-specific growth hormone ELISA Kit
Uniprot No.
Homo sapiens (Human)
Sample Types
serum, plasma, tissue homogenates
Detection Range
133 pg/mL-4000 pg/mL
33 pg/mL
Assay Time
Sample Volume
Detection Wavelength
450 nm
Research Area
Signal Transduction
Assay Principle
Intra-assay Precision (Precision within an assay): CV%<15%      
Three samples of known concentration were tested twenty times on one plate to assess.  
Inter-assay Precision (Precision between assays): CV%<15%      
Three samples of known concentration were tested in twenty assays to assess.    
To assess the linearity of the assay, samples were spiked with high concentrations of human GH2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
  Sample Serum(n=4)  
1:1 Average % 89  
Range % 83-98  
1:2 Average % 90  
Range % 85-97  
1:4 Average % 94  
Range % 90-101  
1:8 Average % 94  
Range % 86-102  

The recovery of human GH2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
Sample Type Average % Recovery Range  
Serum (n=5) 95 89-100  
EDTA plasma (n=4) 93 87-99  

Typical Data
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
pg/ml OD1 OD2 Average Corrected  
4000 2.531 2.447 2.489 2.443  
1666.7 1.295 1.342 1.319 1.273  
666.7 0.628 0.607 0.618 0.572  
266.7 0.285 0.306 0.296 0.250  
133 0.163 0.152 0.158 0.112  
0 0.045 0.047 0.046    

and FAQs
Store at 2-8°C. Please refer to protocol.
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx

This Human GH2 ELISA Kit was designed for the quantitative measurement of Human GH2 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 133 pg/mL-4000 pg/mL and the sensitivity is 33 pg/mL.

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Target Background

(From Uniprot)
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Gene References into Functions
  1. Type 1 diabetic women delivering large for gestational age infants had lower placental GH levels in early pregnancy. PMID: 26589570
  2. genetic association studies in populations in Estonia, Czech Republic, and Bashkortostan/Russia: Data suggest an SNP in GH2 (rs2006123) is associated with adult height (not body mass index); A-allele is associated with taller stature. [META-ANALYSIS] PMID: 24035309
  3. Maternal serum PGH at 11-13 weeks' gestation is unlikely to be a useful biochemical marker for early prediction of small for gestational age neonates. PMID: 22489624
  4. results are consistent with a pleiotropic effect of placental hGH/CSH genes at the maternal-fetal interface relating to the regulation of fetal growth and the risk of affected maternal metabolism. PMID: 22387044
  5. These results suggest that the normal PGH-IGF-I-IGFBP3 axis in pregnancy is abnormal in Type 1 Diabetic pregnancies. PMID: 22363400
  6. early first trimester maternal serum marker for Down syndrome PMID: 19844941
  7. The hGH-V promoter activity and the endogenous mRNA expression in human placental choriocarcinoma cell line JAR in the presence of glucose and demethylating genome conditions, were compared. PMID: 20005926
  8. GH-V plays a major role in affecting target cells expressing the GH receptor, thus potentially exerting significant GH-like effects on maternal physiology during pregnancy. PMID: 12213191
  9. Data show that improved binding affinity of human growth hormone (hGH(v)) results from numerous small contributions distributed broadly over the interface. PMID: 12946357
  10. Using a mutagenesis-scanning analysis of 81 single and 32 pairwise double mutations, it is shown that the GHv hormone's two spatially distal receptor binding sites (Site1 and Site2) are allosterically coupled PMID: 15563602
  11. results offer the first evidence for a placental role of human placental growth hormone(hPGH) and suggest an autocrine/paracrine role of hPGH in the regulation of trophoblast invasion PMID: 15718272
  12. PGH may play a role in the mechanisms of disease in preeclampsia and fetal growth restriction. PMID: 17701665
  13. Placental growth hormone (PGH) secretion by BeWo cells is regulated by hormonal factors and adipokines. Elevated insulin and leptin levels might down-regulate PGH secretion. PMID: 18356738

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Subcellular Location
Protein Families
Somatotropin/prolactin family
Tissue Specificity
Expressed in the placenta.
Database Links

HGNC: 4262

OMIM: 139240

KEGG: hsa:2689

STRING: 9606.ENSP00000333157

UniGene: Hs.406754

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