GH2 Antibody

Code CSB-PA009408LA01HU
Size US$166
Order now
Image
  • Western blot
    All lanes: GH2 antibody at 16µg/ml + Mouse skeletal muscle tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 25, 29, 24, 28 kDa
    Observed band size: 25 kDa

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA009408LA01HU at dilution of 1:100

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GH2 Polyclonal antibody
Uniprot No.
Target Names
GH2
Alternative Names
GH2 antibody; Growth hormone variant antibody; GH-V antibody; Growth hormone 2 antibody; Placenta-specific growth hormone antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Growth hormone variant protein (27-217AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The GH2 Antibody (Product code: CSB-PA009408LA01HU) is Non-conjugated. For GH2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA009408LB01HU GH2 Antibody, HRP conjugated ELISA
FITC CSB-PA009408LC01HU GH2 Antibody, FITC conjugated
Biotin CSB-PA009408LD01HU GH2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Gene References into Functions
  1. Type 1 diabetic women delivering large for gestational age infants had lower placental GH levels in early pregnancy. PMID: 26589570
  2. genetic association studies in populations in Estonia, Czech Republic, and Bashkortostan/Russia: Data suggest an SNP in GH2 (rs2006123) is associated with adult height (not body mass index); A-allele is associated with taller stature. [META-ANALYSIS] PMID: 24035309
  3. Maternal serum PGH at 11-13 weeks' gestation is unlikely to be a useful biochemical marker for early prediction of small for gestational age neonates. PMID: 22489624
  4. results are consistent with a pleiotropic effect of placental hGH/CSH genes at the maternal-fetal interface relating to the regulation of fetal growth and the risk of affected maternal metabolism. PMID: 22387044
  5. These results suggest that the normal PGH-IGF-I-IGFBP3 axis in pregnancy is abnormal in Type 1 Diabetic pregnancies. PMID: 22363400
  6. early first trimester maternal serum marker for Down syndrome PMID: 19844941
  7. The hGH-V promoter activity and the endogenous mRNA expression in human placental choriocarcinoma cell line JAR in the presence of glucose and demethylating genome conditions, were compared. PMID: 20005926
  8. GH-V plays a major role in affecting target cells expressing the GH receptor, thus potentially exerting significant GH-like effects on maternal physiology during pregnancy. PMID: 12213191
  9. Data show that improved binding affinity of human growth hormone (hGH(v)) results from numerous small contributions distributed broadly over the interface. PMID: 12946357
  10. Using a mutagenesis-scanning analysis of 81 single and 32 pairwise double mutations, it is shown that the GHv hormone's two spatially distal receptor binding sites (Site1 and Site2) are allosterically coupled PMID: 15563602
  11. results offer the first evidence for a placental role of human placental growth hormone(hPGH) and suggest an autocrine/paracrine role of hPGH in the regulation of trophoblast invasion PMID: 15718272
  12. PGH may play a role in the mechanisms of disease in preeclampsia and fetal growth restriction. PMID: 17701665
  13. Placental growth hormone (PGH) secretion by BeWo cells is regulated by hormonal factors and adipokines. Elevated insulin and leptin levels might down-regulate PGH secretion. PMID: 18356738

Show More

Hide All

Subcellular Location
Secreted.
Protein Families
Somatotropin/prolactin family
Tissue Specificity
Expressed in the placenta.
Database Links

HGNC: 4262

OMIM: 139240

KEGG: hsa:2689

STRING: 9606.ENSP00000333157

UniGene: Hs.406754

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*