Mouse Cadherin-3(CDH3) ELISA kit

Code CSB-EL005052MO
Size 96T,5×96T,10×96T
Price Request a Quote or Start an on-line Chat
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Target Name
cadherin 3, type 1, P-cadherin (placental)
Alternative Names
Cdh3; Cdhp; Cadherin-3; Placental cadherin; P-cadherin
Abbreviation
CDH3
Uniprot No.
Species
Mus musculus (Mouse)
Sample Types
serum, plasma, tissue homogenates
Detection Range
78 pg/mL-5000 pg/mL
Sensitivity
19.5 pg/mL
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Neuroscience
Assay Principle
quantitative
Measurement
Sandwich
Troubleshooting
and FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx

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Target Background

Function
(From Uniprot)
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Gene References into Functions
  1. P-Cadherin is not required for maintenance of retinal stem cells in vivo. PMID: 28494434
  2. P-cadherin (CDH3) is highly dominant in both mouse and human retinal pigment epithelium in situ. The degree of dominance of P-cadherin is surprisingly large, with mouse Cdh3 and human CDH3 accounting for 82-85% and 92-93% of the total of the three cadherin mRNAs, respectively. PMID: 29338041
  3. P-cadherin is a direct PAX3-FOXO1A transcriptional target involved in Alveolar rhabdomyosarcoma aggressiveness. PMID: 22710718
  4. Loss of P-cadherin is associated with melanoma. PMID: 21445019
  5. UVB exposure resulted in the overexpression of the cytokines, tumour necrosis factor (TNF)-alpha, interleukin (IL)-6 and the adhesion molecule P-cadherin. PMID: 20212509
  6. Truncated P-cadherin promotes melanoma cell invasion and migration and therefore has an important role in the progression of malignant melanoma. PMID: 16919267
  7. P-cadherin is a newly defined transcriptional target gene of p63, with a crucial role in hair follicle morphogenesis as well as the apical ectodermal ridge during limb bud outgrowth in humans whereas it is not required for either in mice. PMID: 18199584

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Database Links
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