Mouse Cholecystokinin,CCK ELISA Kit

1. Study shows that independent of the neurochemical content, cholecystokinin/type 1 cannabinoid receptor-expressing interneurons have similar physiological and morphological properties, providing an endocannabinoid-sensitive synaptic inhibition onto the amygdalar principal neurons. PMID: 28391401
2. In summary, our study is the first to indicate that CCK/CCK-AR pathway is critical and protective against liver I/R injury. The activation of this pathway not only prevents hepatocellular apoptosis, but also reduces inflammatory response by suppressing NF-kappaB. PMID: 28521244
3. CCK/GLP-1 play contributory roles in anorexia induction by trichothecenes T-2 toxin, HT-2 toxin, diacetoxyscirpenol and neosolaniol. PMID: 28964791
4. GPR120-induced incretin glucse-dependent insulinotropic polypeptide secretion is indirectly mediated by cholecystokinin. PMID: 28324023
5. Medullary interstitial cells respond to body fluid expansion by CCK release for feedback regulation of the late proximal tubular reabsorption. PMID: 28298361
6. results suggest that normal integration of CCK+ basket cells in cortical networks is key to support spatial coding in the hippocampus. PMID: 28394324
7. PC7 has a critical role in normal processing of cholecystokinin in mouse brain PMID: 27923657
8. These studies reemphasize the beneficial effects imparted by co-administration of obestatin and CCK8 and their potential use towards countering obesity. PMID: 27032885
9. new information on the cell specific localization of NUCB2/nesfatin-1 in the intestinal mucosa, and a novel function for nesfatin-1 in modulating intestinal CCK and PYY expression and secretion PMID: 26920055
10. Results showed that CCK is important for lipid transport and energy expenditure to control body weight in response to dietary lipid feeding PMID: 26171590
11. SP1 results in a CCK response deficiency that may contribute to the increased meal size and overall hyperphagia in synphillin-1 transgenic mice PMID: 26569394
12. active GLP-1 produced in the islet stimulates cholecystokinin production and secretion in a paracrine manner via cyclic AMP and CREB. PMID: 25984632
13. Data (including data from studies using transgenic mice) suggest that enhanced Cck expression in pancreatic beta-cells protects these cells from the cell-withering effects of aging, apoptotic stress, and (streptozotocin-induced) diabetes type 2. PMID: 26394663
14. total Ca(2+) mobilization evoked by CCK-8 was attenuated by a 30% in the presence of 100 microM melatonin compared with the responses induced by CCK-8 alone. PMID: 25084987
15. Endogenous cholecystokinin is in part responsible for the development and progression of pancreatic cancer. PMID: 25058882
16. octapeptide exerts a direct effect on T cells, which is dependent on cholecystokinin-2 receptor PMID: 24704498
17. Data demonstrate that the ERK pathway is required for CCK-stimulated pancreatic adaptive growth. PMID: 25104499
18. I cells in duodenum are enriched in expression of CCK and ghrelin. PMID: 25004095
19. Data show the transcriptional activation of the cholecystokinin gene by DJ-1 through interaction of DJ-1 with RREB1 and the effect of DJ-1 on the cholecystokinin level. PMID: 24348900
20. This study concluded that CCK is a mediator of dietary fat-associated pancreatic cancer, and it is also involved in the invasiveness of pancreatic tumors. PMID: 24817409
21. CCK enhances cholesterol absorption by activation of a pathway involving CCK1R/CCK2R, Gbetagamma, PI3K, Akt, Rab11a, and NPC1L. PMID: 24692543
22. mouse corneal afferent sensory neurons expressed CCK and GAST, and the CCK1R receptors. PMID: 24576871
23. Gastric PAI-1 modulates vagal effects of cholecystokinin. PMID: 23816469
24. ILDR1 regulates CCK release through a mechanism dependent on fatty acids and lipoproteins. PMID: 23863714
25. hnRNP-K regulates extracellular matrix, cell motility, and angiogenesis pathways. Involvement of the selected genes (Cck, Mmp-3, Ptgs2, and Ctgf) and pathways was validated by gene-specific expression analysis PMID: 23564449
26. CD36 is a major mediator of FA-induced release of CCK and secretin. These peptides contribute to the role of CD36 in fat absorption and to its pleiotropic metabolic effects. PMID: 23233532
27. a lineage of mature enteroendocrine cells have the ability to coexpress members of a group of functionally related peptides: CCK, secretin, GIP, GLP-1, PYY, and neurotensin PMID: 23064014
28. peripheral apo AIV requires an intact CCK system and vagal afferents to activate neurons in the hindbrain to reduce food intake PMID: 23027805
29. These data suggest that a mixture of guar gum and fructo-oligosaccharide can maintain its appetite suppressant effect in fatty media. PMID: 23054308
30. Our data demonstrate that CCK expressed in the basolateral amygdala represents a key brain substrate for anxiogenic and depressant effects of the peptide. PMID: 22613736
31. expression of CCK is increased in hippocampal pyramidal cells in mice with recurrent, spontaneous seizures PMID: 22155653
32. Data suggest that CCK acts to increase glutamatergic transmission to the preproglucagon-positive neurons; this action appears to involve activation of alpha1-adrenergic receptors. PMID: 21885869
33. Simotang enhances the gastrointestinal motility in chronically stressed mice by regulating the serum motilin level and the expression of cholecystokinin. PMID: 21472126
34. Gene expressions of ghrelin, PYY, and CCK was increased in the gastrointestinal tract of the hyperphagic intrauterine growth restriction rat offspring. PMID: 21264794
35. Cholecystokinin signalling is not involved directly in light-induced resetting of the suprachiasmatic nucleus or in regulating its function. PMID: 20731710
36. Short-term DeltaFosB overexpression increases both Cck promoter activity and gene expression. PMID: 20226774
37. Conjugated linoleic acid isoforms are particularly potent CCK secretagogues, which also boost intracellular stores of CCK. PMID: 20352619
38. CCK is up-regulated by islet cells during obesity and functions as a paracrine or autocrine factor to increase beta-cell survival and expand beta-cell mass to compensate for obesity-induced insulin resistance. PMID: 20534724
39. CCK is involved in regulating the metabolic rate and is important for lipid absorption and control of body weight in mice placed on a high-fat diet. PMID: 20117110
40. Lack of CCK induces gallbladder hypomotility that prolongs the residence time of excess cholesterol in the gallbladder, leading to rapid crystallization and precipitation of solid cholesterol crystals. PMID: 19836465
41. role of anorectic effects possibly by enhancing release of pancreatic amylin PMID: 12576089
42. In whole area of hippocampus, NPY-, SOM- (somatostatin), CCK-, and VIP-positive neurons accounted for about 31%, 17%, 7%, and 8% of GABAergic neurons, respectively. PMID: 12746872
43. Intense cholecystokinin immunoreactivity is found in the mossy fiber pathway (stratum lucidum and dentate hilus) and in the inner molecular layer of the dentate gyrus. PMID: 14643757
44. Lack of gastrin impairs gastrin-enterochromaffin-like cell axis, whereas lack of gastrin and CCK impairs both hormonal pathways. In gastrin-CCK double-knockout mice, acid secretion is controlled by cholinergic vagal stimulation, normalizing acid output. PMID: 14762785
45. In this review, tissue-specific processing of cholecystokinin precursor in brain and gut to a large extent can be explained by the roles of prohormone convertases 1 and 2. PMID: 15075450
46. These results indicate that CCK provides an inhibitory influence on GnRH-1 neuronal migration, contributing to the appropriate entrance of these neuroendocrine cells into the brain, and thus represent the first report of a developmental role for CCK PMID: 15152034
47. Psychological stress inhibits the small intestinal transit, probably by down-regulating CCK and up-regulating VIP expression in small intestine. PMID: 15655834
48. Both gastrin and combined gastrin-cholecytokinin deficiency reduced the gastric IAPP and Peptide Yy expression. PMID: 16002530
49. prohormone convertase 2 is important for cholecystokinin processing PMID: 16174778
50. results provide the first direct evidence that prohormone convertase 5 (PC5) is involved in CCK processing PMID: 16266771

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KEGG: mmu:12424

STRING: 10090.ENSMUSP00000035120

UniGene: Mm.2619