Mouse N-terminal pro-brain natriuretic peptide,NT-proBNP ELISA KIT

N-terminal pro-brain natriuretic peptide (NT-proBNP) is a cardiac biomarker released from ventricular cardiomyocytes in response to increased wall tension and volume overload. As the inactive N-terminal fragment of the brain natriuretic peptide precursor, NT-proBNP serves as a stable indicator of cardiac stress. Cardiovascular researchers commonly use this biomarker to measure heart failure, ventricular dysfunction, and cardiac remodeling processes.

This quantitative sandwich ELISA kit detects mouse NT-proBNP in serum and plasma samples with a detection range of 0.156 ng/mL to 10 ng/mL and sensitivity of 0.039 ng/mL. The assay requires 50-100 μL sample volume and can be completed within 1-5 hours, with measurements taken at 450 nm wavelength.

Application Examples

Note: The following application examples are drawn from a selection of publications citing this product. For additional applications, please refer to the full list of references in the "Citations" section.

This ELISA kit has been applied in cardiovascular research to measure cardiac injury and dysfunction through NT-proBNP levels in mouse models. The kit provides a useful tool for evaluating heart damage in experimental studies that examine cardioprotective interventions and drug-induced cardiotoxicity.

• Cardiac injury measurement: Used to evaluate heart damage in mouse models by measuring NT-proBNP as a biomarker of cardiac dysfunction
• Cardiotoxicity studies: Applied in research examining drug-induced cardiac injury and potential protective interventions
• Cardiovascular biomarker research: Used alongside other cardiac markers to comprehensively measure heart function and injury in experimental settings
• Plasma biomarker analysis: Applied for quantitative measurement of NT-proBNP in plasma samples collected from experimental mouse models