Rat anti-Mullerian hormone (AMH) ELISA kit

Specification
Target

Code	CSB-E11162r
See More Details
Product Type	ELISA Kit
Size	96T,5×96T,10×96T
Uniprot No.	P49000
Lead Time	3-5 working days
Abbreviation	AMH
Protein Biological Process 1	Developmental Protein
Target Name	anti-Mullerian hormone
Alias	MIF, MIS, Mullerian inhibiting factor\|Mullerian inhibiting substance
Species	Rattus norvegicus (Rat)
Protein Biological Process 3	Differentiation
Sample Types	serum, plasma, tissue homogenates
Detection Range	0.2 ng/mL-15 ng/mL
Sensitivity	0.1 ng/mL
Assay Time	1-5h
Sample Volume	50-100ul
Detection Wavelength	450 nm
Research Area	Signal Transduction
Protocol	Instructions Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle	quantitative
Measurement	Competitive
Target Details	Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome.
HGNC	464
RGD	2108
MGI	88006
Precision
Linearity
Recovery
Typical Data
References	Suboptimal nutrition in utero causes DNA damage and accelerated aging of the female reproductive tract Aiken CE et al,FASEB J,2013 Jun 21. The Biochemical and Histologic Effects of Adnexal Torsion and Early Surgical Intervention to Unwind Detorsion on Ovarian Reserve An Experimental Study Ozler A et al,Reprod Sci.,2013 Apr 12. Identification of PCSK9 as a novel serum biomarker for the prenatal diagnosis of neural tube defects using iTRAQ quantitative proteomics. An D.et al,Sci Rep.,/ Antimullerian hormone and its receptor gene expression in prenatally androgenized female rats. Daneshian Z.et al,Int J Endocrinol Metab.,13(1):e19511 Kisspeptin is involved in ovarian follicular development during aging in rats Fernandois DD. et al,J Endocrinol,2015 Dec 23. Exposure of Female Rats to an Environmentally-Relevant Mixture of Brominated Flame Retardants Targets the Ovary, Affecting Folliculogenesis and Steroidogenesis Lefvre PL. et al,Biol Reprod,2015 Nov 25. The Effects of Diabetes Mellitus on Ovarian Injury and Reserve: An Experimental Study Nayki U. et al,Gynecol Obstet Invest,2015 Dec 19. Evaluation of the effects of fulvestrant and micronized progesterone on the post-operative adhesion formation and ovarian reserve in rat model with immunohistochemical and biochemical analysis. Oner G. et al,Gynecol Endocrinol,2015 Aug 18:1-6. Resveratrol inhibits inflammatory signaling implicated in ionizing radiation-induced premature ovarian failure through antagonistic crosstalk between silencing information regulator 1 (SIRT1) and poly(ADP-ribose) polymerase 1 (PARP-1) Riham Soliman Said.et al,Biochemical Pharmacology,2016 103:140-50. High-Fat, High-Sugar Diet Disrupts the Pre-ovulatory Hormone Surge and Induces Cystic Ovaries in Cycling Female Rats Katrina M Volk.et al,Journal of the Endocrine Society,Nov 2 Effects of chronic unpredictable mild stress on ovarian reserve in female rats: Feasibility analysis of a rat model of premature ovarian failure Xiao‑Yan Fu.et al,Molecular Medicine Reports,May 8 Assaying Reproductive Capacity in Female Rodents Aiken CE, et al, Methods in Molecular Biology,December 11
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Function	This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
Subcellular Location	Secreted
Protein Families	TGF-beta family
Database Links	KEGG: rno:25378 STRING: 10116.ENSRNOP00000026220 UniGene: Rn.19121
Pathway	cAMP signaling pathway Hippo signaling pathway TGF-beta signaling pathway

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