This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
Gene References into Functions
The study uncovers a new role for AMH in regulating gonadotrope function and suggests that AMH participates in the postnatal elevation of FSH secretion in females. PMID: 27030385
AMH increases GnRH-dependent LH pulsatility and secretion, supporting a central action of AMH on GnRH neurons. PMID: 26753790
Resveratrol reduced antimullerian hormone levels in rat model of polycystic ovary syndrome. PMID: 25667201
AMH is the first hormone/protein shown to have an inhibitory action on primordial follicle assembly. PMID: 21637711
In ovaries from adult cycling rats AMH protein is localized in large primary and secondary follicles and not in primordial or small primary follicles, with its highest expression in the largest preantral follicles. PMID: 20816688