Rat gastric inhibitory polypeptide (Gip) ELISA kit

1. Sitagliptin attenuated resistin expression via the GIP-dependent pathway, which inhibited sympathetic innervation through a signalling pathway involving phosphatidylinositol 3-kinase (PI3K) and Akt protein. PMID: 26811539
2. provide evidence that gastric inhibitory polypeptide regulates skeletal muscle glucose transport; however, the exact signaling mechanism(s) remain unknown PMID: 26041107
3. glucose-dependent insulinotropic polypeptide and Glucose-dependent insulinotropic polypeptide receptors expression in the rat major salivary glands, as well as its variation in the rat SMG during the growth period PMID: 24360021
4. The role of GIP as a critical link between catch-up growth and the development of metabolic disturbances. PMID: 25032669
5. In a HFD model, DPP4-rats exhibited reduced adipose tissue inflammation and improved insulin resistance, which may be mediated in part by GIP induction of adiponectin. PMID: 23408696
6. Changes in the secretion and action of GIP play an important role in metabolic adaptations during pregnancy and especially lactation. PMID: 24236022
7. Dietary fructose elicits GLP-1 secretion without simultaneous release of glucagonotropic GIP. PMID: 24525020
8. Data suggest that secretion of GIP and GLP1 (glucagon-like peptide-1) by enterocytes (in rats with diabetes type 2 and in normal rats) can be up-regulated by dietary factors, here, corn zein hydrolysate as a hypoglycemic dietary supplement. PMID: 23798598
9. Postprandial plasma GIP response is blunted in rats fed chlorogenic acid (a component of coffee), with a lower peak concentration and decreased AUC up to 180 min. PMID: 21977912
10. Plasma glucose and insulin concentrations were not affected by oral fat, but fat-induced Gip secretion was particularly (p < 0.05) increased in insulinoma-bearing rats. PMID: 21851286
11. truncated forms of GIP exhibit potent anti-diabetic actions, without pro-obesity effects, and that the C-terminus contributes to the lipogenic actions of GIP PMID: 20231880
12. Both GIP and GLP-1 outputs responded dose dependently to increasing amounts of dietary carbohydrate but not protein. GIP-secreting cells were more sensitive than GLP-1-secreting cells to changes in intestinal carbohydrate content. PMID: 20522638
13. GIP is expressed in and secreted from pancreatic islets and promotes islet glucose competence and also could support islet development and/or survival. PMID: 20138041
14. GIP, GLP-1, insulin and gastrin have roles in ghrelin release in the isolated rat stomach PMID: 15093702
15. Persistent activation (8 h) of the GIP signalling pathway decreased the GLP (glucagon-like peptide)-1 dependent insulin secretion accompanied by an upregulation of G-protein alphai2 protein level to about 126% PMID: 15376236
16. Hippocampal expression of the gene-encoding varied strongly in parallel with cell-proliferation rates in the adult rat dentate gyrus. PMID: 15716418
17. These results indicate that cell-specific expression of GIPR is associated with the binding of the transcription factors Sp1 and Sp3 to the GIPR promoter. PMID: 16403775
18. Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor PMID: 16476726
19. protein kinase B, LKB1, and AMP-activated protein kinase have roles in activation of lipoprotein lipase by glucose-dependent insulinotropic polypeptide in adipocytes PMID: 17244606
20. Administration of resistin to adipocytes mimicked the effects of GIP on the PKB/LKB1/AMPK/LPL pathway: increasing phosphorylation of PKB, reducing levels of phosphorylated LKB1 and AMPK, and increasing LPL activity. PMID: 17890220
21. data indicate a modest effect of GIP on glucagon secretion from isolated rat islets, which was not observed in vivo PMID: 18163884
22. GATA-4 may function to augment or enhance GIP expression rather than act as an initiator of GIP transcription. PMID: 18343025
23. feeding rats with dietary resistant starch reduced the GIP mRNA levels along the entire length of the jejunoileum in both Wistar and type 2 diabetic GK rats PMID: 18685191
24. Nutrient-driven GIP secretion into intestinal lymph is different between diabetic Goto-Kakizaki rats and Wistar rats. PMID: 19056762
25. oral glucose but not artificial sweetners increased plasma GIP levels approximately 4-fold and GLP-1 levels approximately 2.5-fold postadministration PMID: 19106249
26. Analyses with GIPR-deficient mice suggest a role of GIP/GIPR signal transduction in promoting spontaneous recovery after nerve crush; injury of GIPR-deficient mouse sciatic nerve revealed impaired axonal regeneration. PMID: 19170165
27. Data show that glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 stimulated Akt/protein kinase B in the INS-1 beta-cell line and isolated mouse islets via a mechanism that did not require phosphoinositide 3-kinase. PMID: 19233842
28. GIP secretion into lymph is stimulated dose dependently by dietary lipids. PMID: 19520739

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KEGG: rno:25040

STRING: 10116.ENSRNOP00000008481

UniGene: Rn.10446