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Rat kininogen(KNG) ELISA Kit

Citations (1) MSDS
Code CSB-E12725r
Size 96T,5×96T,10×96T
Price Request a Quote or Start an on-line Chat
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Target Name
kininogen 1
Alternative Names
Kng1 ELISA Kit; Kng ELISA Kit; Kininogen-1 [Cleaved into: Kininogen-1 heavy chain; Bradykinin; Kininogen-1 light chain] ELISA Kit
Abbreviation
KNG1
Uniprot No.
P08934
Species
Rattus norvegicus (Rat)
Sample Types
Detection Range
Sensitivity
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Cardiovascular
Assay Principle
quantitative
Measurement
Sandwich
Precision
 
Linearity
 
Recovery
 

Typical Data
 
ELISA Data Analysis
ELISA Standard Curve & Curve Expert software
Troubleshooting
and FAQs
ELISA kit FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx

Citations

Related Products

Kng1 antibodies

Kng1 Proteins

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Customer Reviews and Q&A

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Target Background

Function
(From Uniprot)
(1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Gene References into Functions
  1. High-molecular-weight kininogen and its peptide fragments modulate arterial thrombosis after arterial injury. PMID: 17293494
Subcellular Location
Secreted, extracellular space.
Tissue Specificity
Plasma.
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Related pathways
Complement and coagulation cascades
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