Recombinant Human Pleiotrophin protein(PTN) (Active)

Code CSB-AP002931HU
Product Type Growth Factor
Size Pls inquiry other sizesPurchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P21246
Image
Storage Buffer 0.2 m filtered PBS, pH 7.4 ,lyophilized
Alias PTN, HBBM, Heparin-binding growth factor 8, HBGF-8, Heparin-binding growth-associated molecule
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The biological activity was measured by its ability to enhance neurite outgrowth of E16?E18 rat embryonic cortical neurons, when neurons were plated on 96 well culture plates that had been pre?coated with 100 ?l/well of a solution of 5?10 ug/ml rHuPTN.
Purity >96% as determined by SDS?PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD
Research Area Immunology
Source E.coli
Gene Names PTN
Expression Region 33-168aa
Product Info Tag-Free
Mol. Weight 15.3 kDa
Protein Description Full Length of Mature Protein
PubMed ID 1701634; 2270483; 1768439; 1457401; 8484754; 9299545; 14702039; 12690205; 15489334; 2388713; 1733956; 8241100; 8484780; 11278720; 20873783
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Function Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells
Subcellular Location Secreted
Protein Families Pleiotrophin family
Tissue Specificity Osteoblast and brain.
Database Links

HGNC: 9630

OMIM: 162095

KEGG: hsa:5764

STRING: 9606.ENSP00000341170

UniGene: Hs.371249

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