CBX5 Monoclonal Antibody

Datasheet
Code CSB-MA172847
Size US$167
Image
  • Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using HP-1 α Mouse mAb diluted at 1:200

  • Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using HP-1 α Mouse mAb diluted at 1:200

  • Immunohistochemical analysis of paraffin-embedded Human Placenta Tissue using HP-1 α Mouse mAb diluted at 1:200

  • Western blot analysis of 1) Hela Cell Lysate, 2)3T3 Cell Lysate, 3) PC12 Cell Lysate using HP-1γα Mouse mAb diluted at 1:1000.

Product Details

Uniprot No. P45973
Alternative Names Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Raised in Mouse
Species Reactivity Human,Mouse,Rat
Immunogen Recombinant Protein
Conjugate Non-conjugated
Purification Method The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form Liquid
Tested Applications ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:50-1:500
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Target Data

Function Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Subcellular Location Nucleus, Chromosome, Chromosome, centromere
Database Links

HGNC: 1555

OMIM: 604478

KEGG: hsa:23468

STRING: 9606.ENSP00000209875

UniGene: Hs.349283

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