CD8A Monoclonal Antibody,PE-Cy5 Conjugated

Datasheet
Code CSB-MA985168
Product Type Monoclonal Antibody
Size US$361
Immunogen
Raised in Mouse
Species Reactivity Human
Specificity
Tested Applications ELISA,IF,FC;Recommended dilution:IF:1:100-1:200
Relevance

 COV8 reacts with the 32 kDa a chain of CD8. This molecule is expressed on the T suppressor/cytotoxic cell population (which comprises about 1/3 of the peripheral blood T lymphocytes total population) and with most of thymocytes, as well as a subset of NK cells. CD8 expresses as either a heterodimer with the CD8b chain (CD8ab) or as a homodimer (CD8aa or CD8bb). CD8 acts as a co-receptor with MHC Class I restricted TCRs in antigen recognition. CD8 function is important for positive selection of MHC Class I restricted CD8+ T cells during T cell development.

* Ratio of CD4 and CD8 is important for monitor of HIV infection.
 
1. Engleman EG et al. (1981) J Exp Med 153: 193-198.
2. Haynes, B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.
3. Parnes, JR. et al. (1989). Adv. Immunol. 44,256-311.
4. Bikah G. et al. (1996). Science  274:1906.
Form Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Isotype IgG1
Clonality Monoclonal
Protocols ELISA Protocol
Immunofluorescence (IF) Protocol
Flow Cytometry (FC) Protocol
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Still Have Questions? Leave a Message or Start an on-line Chat

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 25,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now!

We don't deal in spam.